parp inhibitors

Acantha Tab (Olaparib 20 mg) is an oral anti-cancer medicine containing Olaparib, a targeted therapy classified as a PARP (Poly ADP-Ribose Polymerase) inhibitor. It works by blocking PARP enzymes that cancer cells use to repair damaged DNA. By preventing DNA repair, Olaparib causes cancer cells—especially those with BRCA1, BRCA2, or other homologous recombination repair (HRR) gene mutations—to die while helping slow the growth and spread of the disease. This medicine is prescribed by oncologists for the treatment of selected ovarian, fallopian tube, primary peritoneal, breast, pancreatic, and prostate cancers, depending on the patient's genetic profile and treatment history. It may be used as maintenance therapy after chemotherapy or as treatment for advanced or recurrent cancers in eligible patients. Key Benefits Targeted PARP inhibitor therapy Helps slow cancer progression in eligible patients Effective in cancers with BRCA or HRR gene mutations Oral tablet for convenient administration May improve progression-free survival when used as prescribed How It Works Olaparib inhibits PARP enzymes responsible for repairing damaged DNA inside cancer cells. Cancer cells with defective BRCA or HRR genes cannot effectively repair DNA without PARP, leading to accumulation of DNA damage and eventual cancer cell death. Administration Take Acantha Tab (Olaparib 20 mg) exactly as prescribed by your oncologist. Swallow the tablet whole with water, with or without food. Do not crush, chew, or split the tablet unless specifically instructed by your healthcare provider. Possible Side Effects Common side effects may include: Nausea or vomiting Fatigue or weakness Anemia Decreased appetite Diarrhea Headache Low blood cell counts Seek immediate medical attention if you develop persistent fever, unusual bleeding, severe shortness of breath, or signs of infection. Precautions Use only under the supervision of a qualified oncologist. Regular blood tests are required during treatment. Avoid pregnancy during therapy and use effective contraception as advised. Inform your doctor about all medicines and supplements you are taking to reduce the risk of drug interactions. Avoid grapefruit and grapefruit juice during treatment, as they may increase Olaparib levels in the body.