msd pharmaceuticals pvt ltd

Janumet is a combination oral antidiabetic medication containing Metformin Hydrochloride and Sitagliptin, designed to help manage blood glucose levels in adults with Type 2 Diabetes Mellitus. It combines two complementary mechanisms of action to improve glycemic control when diet, exercise, and metformin alone are not sufficient. Key Benefits Helps lower and maintain healthy blood sugar levels. Combines two proven antidiabetic medicines in a single tablet for convenient dosing. Improves both fasting and post-meal blood glucose control. Supports long-term diabetes management when used alongside a healthy diet and regular physical activity. May reduce the need for multiple diabetes medications in appropriate patients. How It Works Metformin decreases glucose production by the liver, reduces intestinal glucose absorption, and improves insulin sensitivity. Sitagliptin is a DPP-4 inhibitor that increases incretin hormone activity, helping the body release more insulin after meals and reducing excess glucose production by the liver. Uses Janumet is prescribed for the treatment of Type 2 Diabetes Mellitus in adults to: Improve blood sugar control when diet and exercise alone are insufficient. Replace separate metformin and sitagliptin tablets with a single combination tablet. Be used with other antidiabetic medications, including insulin or sulfonylureas, when recommended by a healthcare provider. Available Strengths Common tablet strengths include: 50 mg Sitagliptin / 500 mg Metformin 50 mg Sitagliptin / 850 mg Metformin 50 mg Sitagliptin / 1000 mg Metformin Possible Side Effects Some patients may experience: Nausea Diarrhea Stomach discomfort Headache Upper respiratory tract infection Low blood sugar (especially when used with insulin or sulfonylureas) Seek immediate medical attention if symptoms of lactic acidosis, severe allergic reactions, or pancreatitis occur. Precautions Use only under medical supervision. Not indicated for Type 1 Diabetes Mellitus or diabetic ketoacidosis. Kidney function should be assessed before and during treatment. Take with meals to reduce gastrointestinal side effects. Inform your healthcare provider about all medications and medical conditions before starting therapy. Storage Store below 25°C in a cool, dry place away from moisture, heat, and direct sunlight. Keep out of reach of children. Disclaimer: This information is intended for educational purposes only and should not replace professional medical advice. Janumet should be used only under the guidance of a qualified healthcare provider.