
Lenalidomide Mechanism of Action: How This Cancer Drug Fights Blood Disorders
Lenalidomide is a powerful and widely used drug in the treatment of multiple myeloma, myelodysplastic syndromes (MDS), and mantle cell lymphoma. But how exactly does it work inside the body to slow down or stop the progression of these blood cancers?
In this blog, we break down the mechanism of action of Lenalidomide in simple termsβand explain why it's one of the most prescribed cancer medications available at MedIndia Dropshipper.
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π¬ What is Lenalidomide?
Lenalidomide is an immunomodulatory drug (IMiD) developed from thalidomide. Itβs sold under brand names such as Revlimid, Lenalid (Natco), and Ciplaβs Lenalidomideβall available through our online pharmacy.
It has anticancer, anti-inflammatory, and immune-boosting properties, making it an essential part of many chemotherapy regimens.
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π§ͺ Mechanism of Action: How Lenalidomide Works
Lenalidomide works through multiple pathways:
1. Immune System Modulation
Lenalidomide boosts the immune system by:
β’ Increasing the activity of T cells and natural killer (NK) cells
β’ Promoting the destruction of abnormal cancer cells
2. Anti-Angiogenesis
It blocks the formation of new blood vessels (angiogenesis), which tumors need to grow and spread.
3. Direct Tumor Suppression
Lenalidomide directly interferes with tumor cell proliferation, causing:
β’ Cell cycle arrest (stopping cancer cells from dividing)
β’ Apoptosis (programmed cell death)
4. Cereblon Pathway Activation
Lenalidomide binds to a protein called cereblon, part of the CRL4 E3 ubiquitin ligase complex. This causes degradation of key proteins (IKZF1 and IKZF3), which are necessary for survival of myeloma cells.
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Result: Cancer cells die, immune function improves, and tumor growth is halted.
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π Diseases Treated with Lenalidomide
β’ Multiple Myeloma
β’ Myelodysplastic Syndromes (MDS)
β’ Mantle Cell Lymphoma
β’ Follicular Lymphoma
β’ Chronic Lymphocytic Leukemia (CLL)
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π Why Buy Lenalidomide from MedIndia Dropshipper?
β’ βοΈ 100% Genuine Products
β’ βοΈ Affordable Pricing on Global Generics
β’ βοΈ Brands like Natco, Cipla, and Celgene Available
β’ βοΈ Secure International Shipping
β’ βοΈ Prescription Support & Pharma-Expert Assistance
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π Order Lenalidomide Now from MedIndia Dropshipper
If you or your patient requires high-quality Lenalidomide, look no further. We provide FDA-approved generics and branded medications at competitive prices.
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, Germany , Switzerland, Japan, United Kingdom, Israel, South Korea, France, Canada, Singapore, China, Turkey, Spain, Australia and Many more You Book Order with us.
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