Augmentin 625mg combines Amoxicillin — a broad-spectrum penicillin — with Clavulanic Acid, a beta-lactamase inhibitor that neutralises the enzymes many bacteria use to destroy Amoxicillin. This combination restores effectiveness against resistant organisms, making it one of the most versatile antibiotics in London's GP and hospital formularies.
London's NHS GPs prescribe Augmentin for sinusitis, otitis media (ear infections), lower respiratory tract infections, skin and soft tissue infections, UTIs, and dental infections. The Clavulanic Acid component is particularly important for treating infections caused by beta-lactamase producing bacteria such as H. influenzae and Moraxella catarrhalis — organisms commonly implicated in ENT infections in London's paediatric and adult populations.
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❓ Why must Augmentin be taken with food and what happens if I take it on an empty stomach?
Taking Augmentin with food significantly reduces the most common side effect — gastrointestinal upset, including nausea, vomiting, and diarrhoea — caused primarily by the Clavulanic Acid component irritating the gut lining. Food slows gastric emptying, allowing the drug to be absorbed more gently and reducing direct contact with the stomach wall. Taking it on an empty stomach markedly increases the chance of stomach upset, which can lead patients to stop the course early. Always take Augmentin at the start of a meal for best tolerability.
