Arpimune ME 25mg Capsule is an immunosuppressive medication containing Cyclosporine (25 mg) in a microemulsion formulation (ME) for enhanced absorption. It works by lowering the activity of the body's immune system. Important Warnings & Precautions Grapefruit Caution: Avoid consuming grapefruit or grapefruit juice while taking this medication, as it significantly increases cyclosporine levels in the blood and raises the risk of toxicity. Infection Risk: Suppressing the immune system makes you more vulnerable to severe infections. Report any fever, chills, or persistent sore throat immediately. Monitoring Required: Regular blood tests are essential to monitor kidney function, liver function, blood pressure, and blood cyclosporine levels to ensure safe dosing.